Clinical studies and medical documentation

All clinical trials conducted at the hospital are listed and described on the GPR Hospital website under the “Clinical Trials” section. This allows patients to get an overview of the clinical trials offered at the GPR Hospital.

If interested, they can contact their treating physician or the “Research and Innovation” department directly. However, patients may also be approached by their physician about participating in a clinical trial.

Internal medicine (urinary tract, intestines, lungs, stomach, other)

Overview of Studies

Clinical Presentation	Study Name	Study Description	Information

RSV Vaccination for Children	HARMONIE	RSV Research Study for Babies	Information Sheet
Urothelial Carcinoma	AVENUE	Non-interventional study for patients with locally advanced and/or metastatic urothelial carcinoma	Information Sheet
Renal Cell Carcinoma/Urothelial/ Bladder Carcinoma	CARAT	Clinical platform for research into molecular alterations and the treatment of renal cell carcinoma (mRCC)	Fact Sheet
Prostate Cancer	PROceed	A prospective, non-interventional study to investigate the clinical data and characteristics of patients with metastatic castration-resistant prostate cancer	Fact Sheet
Non-small cell lung cancer	FINN	A Germany-wide prospective, multicenter observational study of first-line therapy with nivolumab and ipilimumab in combination with two cycles of chemotherapy in patients with metastatic non-small cell lung cancer	Information sheet
Advanced hematologic diseases or solid tumors	INFINITY	Clinical research platform for capturing decision-making in biomarker-based precision oncology and its clinical significance	Information sheet
Rheumatoid Arthritis	LEF15	Rheumatoid arthritis in routine clinical practice. The study is a non-interventional observational study and has no influence on the treatment method prescribed by the physician	Information Sheet
Gastrointestinal Tumors	PLATON	A multicenter, prospective observational study to evaluate genetic tumor profiles and associated treatment decisions in the oncology of gastrointestinal tumors	Information sheet
Colon Cancer	COMPASS	Randomized, controlled, parallel-group study, open-label, multicenter	Information sheet
Orthopedics - Hip Surgery - Thrombosis Prevention	ENABLE-HIP	Multicenter randomized study on shortened anticoagulation and increased mobilization after hip surgery	Information sheet
Esophageal and Gastric Cancer	SAPHIR	Non-interventional study for patients with esophageal and gastric cancer	Information sheet
Pediatric Clinic - Obesity	WEGIO	Multicenter, diagnostic, and observational study on childhood obesity	Information sheet
Surgery - Hernias	Herniamed	Herniamed Quality Assurance Study	Information sheet

Cardiology (heart)

Overview of Studies

Clinical Presentation	Study Name	Study Description	Information
Atrial high-frequency episode	NOAH-AFNET 6	New oral anticoagulants in patients with high-frequency atrial episodes	Information sheet
Atherosclerotic cardiovascular disease and elevated lipoprotein(a)	ACCLAIM-Lp(a)	This is a current Phase III study investigating the effect of the drug lepodisiran on the reduction of serious adverse cardiovascular events in adults with elevated lipoprotein(a)	Information sheet
Acute Coronary Syndrome (ACS)	AEGIS II	A randomized, double-blind, placebo-controlled, multicenter, parallel-group study (Phase 3 clinical trial) to evaluate the efficacy and safety of CSL112 in patients with acute coronary syndrome (ACS).	Fact Sheet

Breast Cancer Center and Gynecological Cancer Center

Overview of Studies

Clinical Presentation	Study Name	Study Description	Information
Breast Cancer	OPAL	Study for patients with breast cancer. Treatment data and questionnaires will be collected from the patients. This is an observational study and will not influence the treatment method prescribed by the doctor.	Information Sheet
Breast Cancer	PERFORM	An epidemiological, prospective observational study to investigate the actual care received by patients with HR+/HER2- negative breast cancer who are treated in the first line with an endocrine-based palbociclib combination therapy according to current treatment standards	Information Sheet
Breast Cancer	PRO B	This study is an observational study of patients with metastatic breast cancer.	Information sheet
Breast Cancer	CAPTOR-BC	Study for patients with breast cancer to document the combination of rivociclib and endocrine therapy	Information sheet
Breast Cancer	CAMBRIA 1	An open-label, randomized Phase III study to evaluate the efficacy and safety of extended therapy with camizestrant	Information sheet
Breast Cancer	FLAMINGO 1	A clinical, randomized, multicenter Phase III adjuvant immunization study with GLSI-100 to prevent the recurrence of breast cancer in HER2+ and HLA-A*02 patients	Fact Sheet
Breast Cancer	MINERVA	Study for patients with breast cancer. National "first-line" Phase IV study to evaluate the safety, efficacy, and quality of life of treatment with abemaciclib plus an aromatase inhibitor or fulvestrant	Information sheet
Ovarian/Endometrial Cancer	SMARAGD	National, prospective, open-label, longitudinal, non-interventional, multicenter observational study (tumor registry).	Information sheet